Glasses-- May compress the nasal bridge, especially harmful for teenagers who are experiencing physical growth.
Contact lenses-- May result in eye infection.
Operation-- May cause sequela like dry eye.
The efficacy of adenosine receptor (ADOR) antagonists in mitigating the progression of myopia has been demonstrated in both human subjects and animal models [2].
Among them, intake of 7-methylxanthine (7-MX) is associated with efficacy of alleviating school myopia in children[3], which is proven as a non-toxic and effective compound to reduce myopia progression and axial eye growth in both pre-clinical and clinical studies[4].
7-MX is one of the ideal compounds for orally administered treatments, which usually have considerably preventive effects on progressive myopia without side effects [5,6].
Lofty price is a significant factor limiting the entry of 7-MX into the public's view.
Another aspect to consider is the appropriate form to adopt in order to make 7-MX enter the market and get consumers’ favor.
The biomanufacturing process to convert caffeine into 7-MX has a great potential to decrease the cost of 7-MX production.
Combining 7-MX with coffee, an internationally popular beverage in the modern society, has the potential to provide individuals, particularly teenagers, with the opportunity to prevent their myopia development when enjoying coffee’s delicacy.